Frequently asked questions.

Clinical and instrumental tests performed on the original X115® New Generation Skin Care formula showed early improvements in skin hydration and a progressive increase in collagen density over four to eight weeks. The study was conducted on the previous formula, not on the current X115® +PLUS⁴; its numerical results must therefore not be transferred automatically to the product sold today.

The current formula is a later and more complete evolution, but individual results still depend on age, initial skin condition, diet, sun exposure, lifestyle and regular use. Fine lines caused by dehydration and overall skin comfort may improve sooner, whereas changes involving deeper skin structures generally require several weeks. No cosmetic or food supplement can guarantee a major reduction in deep wrinkles.

Read the full explanation of the historical clinical study.

Yes. X115 skincare products and supplements can also be used separately. The supplement works from within by supplying selected nutrients, while the cosmetics act topically on hydration, comfort and the visible quality of the skin.

The IN & OUT protocol combines the two approaches because they are complementary, but it is not compulsory to use both from the first day. The routine can be adapted to individual needs, preferences and budget.

For X115® +PLUS⁴, the current guidance is a cycle of about 30 days for younger skin or skin with fewer signs of ageing, extending to 90 days for mature skin or skin with greater needs. Afterwards, the routine may continue with X115® PRIMARY, with +PLUS⁴ on alternate days, or with periodic intensive cycles.

Skincare products may be used continuously throughout the year. In the case of prolonged supplementation, medical conditions, pregnancy, breastfeeding or concurrent use of medicines and other supplements, the routine should be discussed with a doctor or pharmacist.

The X115® brand was created in 2011 with the aim of combining advanced skincare and nutricosmetics in a coordinated IN & OUT protocol.

The +PLUS line was introduced in 2018 and subsequently updated: +PLUS² in 2020, +PLUS³ in 2022 and the current +PLUS⁴ in 2025. The present formula provides 5 g of hydrolysed collagen from four certified sources, 120 mg of total hyaluronic acid and a broader DAY & NIGHT complex that includes silicon, chondroitin sulphate, ceramides, probiotics and antioxidants.

These successive versions are formulation evolutions. They do not mean that clinical results obtained with an earlier formula can be presented as if they had been measured directly on +PLUS⁴.

No. X115® +PLUS⁴ contains collagen of animal origin and is therefore not suitable for vegetarians or vegans. Its 5 g daily dose combines:

• 2,300 mg Naticol® hydrolysed fish-skin collagen;
• 1,500 mg Verisol® B hydrolysed bovine-skin collagen;
• 1,000 mg Chondractiv® collagen from chicken sternal cartilage;
• 200 mg Prosagen® Si hydrolysed fish-skin collagen with orthosilicic acid.

X115® +PLUS⁴ FISH contains only marine collagen, but it is still not vegetarian or vegan. Products marketed as “plant collagen” do not contain collagen itself; they generally contain plant-derived amino acids or other substances intended to support collagen synthesis.

The DAY vial contains alpha-lipoic acid and approximately 2 g of fructose. Anyone with diabetes or pre-diabetes, and especially anyone taking glucose-lowering medicines, should obtain medical advice before use.

The supplement must not be used to change or reduce prescribed medication without the treating doctor’s instructions.

People receiving ongoing medical treatment should ask their doctor or pharmacist before starting the supplement. This is particularly important with glucose-lowering medicines and whenever several medicines or supplements are taken together.

A universal separation interval cannot be prescribed for every medicine: the appropriate timing depends on the specific treatment.

A general FAQ cannot establish whether a supplement is appropriate for a specific thyroid or liver condition. Before use, show the complete ingredient list and nutrition table to the doctor who knows the diagnosis, current tests and medication.

The same precaution applies to any significant or chronic medical condition.

A small amount of sediment may occur because the liquid contains plant extracts and the liquid does not need to be perfectly clear like a filtered beverage. After activating the reservoir cap, shake the vial vigorously for a few seconds and drink it immediately.

Do not use the product if the package is damaged, the seal is not intact, the vial is swollen or leaking, the expiry date has passed, or the colour and smell are clearly abnormal. In those cases, contact customer support and provide the batch number.

Adding sugar is unnecessary. The NIGHT sachet can be dissolved in water or another cold or lukewarm drink. The DAY vial may be taken as it is or diluted in a small amount of water after activation and shaking.

A cool drink and a greater volume of water can make the flavour milder without altering the recommended daily dose. Do not mix the product into hot liquids.

Minor variations can occur because the formula contains plant extracts and because raw materials or excipients may be refined over time to improve taste, solubility or stability.

A slight difference is not in itself a sign of deterioration. Marked changes, an abnormal smell, leakage, swelling or a damaged seal should instead be reported to customer support with the batch number and photographs.

Yes. X115® supplements are manufactured and packaged in Italy in specialised facilities and are notified to the Italian Ministry of Health in accordance with the legislation applicable to food supplements.

Notification is a regulatory requirement; it is not a medicinal-product authorisation and does not mean that the Ministry has certified a therapeutic effect.

Yes. MAN-WOMAN is not reserved exclusively for men. It is a lightweight, fast-absorbing cream-gel designed for oily, combination or male skin and for early wrinkles. It may therefore suit women who prefer a lighter, drier finish or whose skin tends to become shiny.

Yes. WOMAN is a richer, more nourishing face cream intended for dry, mature or stressed skin. It can also be used by men whose skin needs greater comfort and a richer texture. The most useful criterion is the skin’s condition, not the user’s gender.

X115 face creams are anti-age skincare products, not sunscreens. During significant sun exposure, apply a broad-spectrum sunscreen suitable for your skin type and renew it according to its instructions.

Antioxidants and anti-age ingredients do not replace an adequate SPF. Sun protection remains essential because ultraviolet radiation is one of the main factors that accelerate visible skin ageing.

No. X115® finished cosmetic products are not tested on animals. Their safety is assessed using permitted methods, raw-material documentation and the procedures required by European cosmetics legislation.

Yes. X115® products are developed by Jarmy s.r.l. and manufactured and packaged in Italy by specialised production partners under the company’s specifications and quality controls.

Free samples are not sent routinely. A very small sample is not sufficient to assess the effects of a supplement or of a structured skincare routine. Any trial sizes, gifts or promotional products available at a given time are shown clearly in the offer or in the shopping cart.

Orders placed on X115.eu are delivered to the European Union countries enabled at checkout. Sales and delivery are not currently available to non-EU destinations through this store.

The available countries and shipping costs are displayed before payment, so the checkout information should be treated as the current reference.